• xmlui.mirage2.page-structure.header.title
    • français
    • English
  • Help
  • Login
  • Language 
    • Français
    • English
View Item 
  •   BIRD Home
  • LAMSADE (UMR CNRS 7243)
  • LAMSADE : Publications
  • View Item
  •   BIRD Home
  • LAMSADE (UMR CNRS 7243)
  • LAMSADE : Publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Browse

BIRDResearch centres & CollectionsBy Issue DateAuthorsTitlesTypeThis CollectionBy Issue DateAuthorsTitlesType

My Account

LoginRegister

Statistics

Most Popular ItemsStatistics by CountryMost Popular Authors
Thumbnail - Request a copy

Storage time does not modify the gene expression profile of cryopreserved human metaphase II oocytes

Stigliani, Sara; Moretti, Stefano; Anserini, Paola; Casciano, Ida; Venturini, Pier Luigi; Scaruffi, Paola (2015), Storage time does not modify the gene expression profile of cryopreserved human metaphase II oocytes, Human reproduction, 30, 11, p. 2519-2526. 10.1093/humrep/dev232

Type
Article accepté pour publication ou publié
Date
2015
Journal name
Human reproduction
Volume
30
Number
11
Pages
2519-2526
Publication identifier
10.1093/humrep/dev232
Metadata
Show full item record
Author(s)
Stigliani, Sara

Moretti, Stefano cc
Laboratoire d'analyse et modélisation de systèmes pour l'aide à la décision [LAMSADE]
Anserini, Paola

Casciano, Ida

Venturini, Pier Luigi

Scaruffi, Paola
Abstract (EN)
STUDY QUESTION Does storage time have any impact on the transcriptome of slowly frozen cryopreserved human metaphase II (MII) oocytes? SUMMARY ANSWER: The length of cryostorage has no effect on the gene expression profile of human MII oocytes. WHAT IS KNOWN ALREADY: Oocyte cryopreservation is a widely used technique in IVF for storage of surplus oocytes, as well as for fertility preservation (i.e. women undergoing gonadotoxic therapies) and oocyte donation programs. Although cryopreservation has negative impacts on oocyte physiology and it is associated with decrease of transcripts, no experimental data about the effect of storage time on the oocyte molecular profile are available to date. STUDY DESIGN, SIZE, DURATION: This study included 27 women, ≤38 years aged, without any ovarian pathology, undergoing IVF treatment. Surplus MII oocytes were donated after written informed consent. A total of 31 non-cryopreserved oocytes and 68 surviving slow-frozen/rapid-thawed oocytes (32 oocytes cryostored for 3 years and 36 cryostored for 6 years) were analyzed.
Subjects / Keywords
human MII oocyte; slow freezing cryopreservation; storage time; microarray; gene expression

Related items

Showing items related by title and author.

  • Thumbnail
    Identification of low intratumoral gene expression heterogeneity in neuroblastic tumors by genome-wide expression analysis and game theory 
    Tonini, Gian Paolo; Bonassi, Stefano; Stigliani, Sara; Cavazzana, Andrea; Di Cristofano, Claudio; Truini, Mauro; Coco, Simona; Moretti, Stefano; Scaruffi, Paola; Albino, Domenico (2008) Article accepté pour publication ou publié
  • Thumbnail
    Bone marrow of neuroblastoma patients shows downregulation of CXCL12 expression and presence of IFN signature 
    Parodi, Stefano; Moretti, Stefano; Garaventa, Alberto; Zanazzo, Giulio; Bonassi, Stefano; Fardin, Paolo; Pistoia, Vito; Tonini, Paolo; Corrias, Maria Valeria; Morandi, Fabio; Gallo, Fabio; Scaruffi, Paola; Stigliani, Sara (2012) Article accepté pour publication ou publié
  • Thumbnail
    Bone Marrow-Infiltrating Human Neuroblastoma Cells Express High Levels of Calprotectin and HLA-G Proteins 
    Morandi, Fabio; Scaruffi, Paola; Gallo, Fabio; Stigliani, Sara; Moretti, Stefano; Bonassi, Stefano; Gambini, Claudio; Mazzocco, Katia; Fardin, Paolo; Haupt, Riccardo; Pistoia, Vito; Tonini, Gian Paolo; Corrias, Maria Valeria (2012) Article accepté pour publication ou publié
  • Thumbnail
    Age-dependent accumulation of genomic aberrations and deregulation of cell cycle and telomerase genes in metastatic neuroblastoma 
    Coco, Simona; Theissen, Jessica; Scaruffi, Paola; Stigliani, Sara; Moretti, Stefano; Oberthuer, André; Valdora, Francesca; Fischer, Matthias; Gallo, Fabio; Hero, Barbara; Bonassi, Stefano; Berthold, Frank; Tonini, Gian Paolo (2012) Article accepté pour publication ou publié
  • Thumbnail
    Transcribed-ultra conserved region expression is associated with outcome in high-risk neuroblastoma 
    Scaruffi, Paola; Stigliani, Sara; Moretti, Stefano; Coco, Simona; Valdora, Francesca; Garaventa, Alberto; Bonassi, Stefano; Tonini, Gian Paolo (2009) Article accepté pour publication ou publié
Dauphine PSL Bibliothèque logo
Place du Maréchal de Lattre de Tassigny 75775 Paris Cedex 16
Phone: 01 44 05 40 94
Contact
Dauphine PSL logoEQUIS logoCreative Commons logo