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hal.structure.identifierService de Génétique Moléculaire et Clinique
dc.contributor.authorCalender, Alain
hal.structure.identifierInstitut de Recherche Interdisciplinaire en Sciences Sociales [IRISSO]
dc.contributor.authorCavalin, Catherine
HAL ID: 741563
hal.structure.identifierPneumologie Pédiatrique
dc.contributor.authorClement, Annick
hal.structure.identifierCentre d'études européennes et de politique comparée [CEE]
dc.contributor.authorMacchi, Odile
hal.structure.identifierPhysiopathologie des maladies génétiques d'expression pédiatrique
dc.contributor.authorNathan, Nadia
hal.structure.identifierImmunovirologie et polymorphisme génétique
dc.contributor.authorPacheco, Yves
hal.structure.identifierCentre d'études européennes et de politique comparée [CEE]
dc.contributor.authorRosental, Paul-André
hal.structure.identifier
dc.contributor.authorSileo, Chiara
hal.structure.identifierService des maladies respiratoires
dc.contributor.authorValeyre, Dominique
dc.date.accessioned2019-04-27T08:47:59Z
dc.date.available2019-04-27T08:47:59Z
dc.date.issued2019
dc.identifier.issn15260542
dc.identifier.urihttps://basepub.dauphine.fr/handle/123456789/18860
dc.language.isoenen
dc.subjectdiseaseen
dc.subject.ddc305en
dc.titlePaediatric sarcoidosisen
dc.typeArticle accepté pour publication ou publié
dc.description.abstractenPaediatric sarcoidosis is an extremely rare disease characterized by a granulomatous inflammation. The estimated incidence is 0.6–1.02/100,000 children, but in the absence of international registers, the disease is probably under-reported. Its pathophysiologic basis is not clearly understood but the current hypothesis is a combination of a genetic predisposition and an environmental exposure that could be either organic or mineral. Contrary to adult forms of the disease, general symptoms are often at the forefront at diagnosis. In its most frequent form, paediatric sarcoidosis is a multi-organ disorder affecting preferentially the lungs, the lymphatic system and the liver, but all organs can be affected. This review aims to provide an overview of current knowledge on sarcoidosis in children, providing a summary of the data available from cohort studies on the presentation, the management and the evolution of the disease in this specific population.en
dc.relation.isversionofjnlnamePaediatric Respiratory Reviews
dc.relation.isversionofjnlvol29en
dc.relation.isversionofjnldate2019
dc.relation.isversionofjnlpages53-59en
dc.relation.isversionofdoi10.1016/j.prrv.2018.05.003en
dc.subject.ddclabelStructure de la sociétéen
dc.relation.forthcomingnonen
dc.relation.forthcomingprintnonen
dc.description.ssrncandidatenonen
dc.description.halcandidateouien
dc.description.readershiprechercheen
dc.description.audienceInternationalen
dc.relation.Isversionofjnlpeerreviewednonen
dc.relation.Isversionofjnlpeerreviewednonen
dc.date.updated2019-04-27T08:18:52Z
hal.identifierhal-02112883*
hal.version1*
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