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hal.structure.identifierNational Cancer Research Institute
dc.contributor.authorStigliani, Sara
hal.structure.identifierLaboratoire d'analyse et modélisation de systèmes pour l'aide à la décision [LAMSADE]
dc.contributor.authorMoretti, Stefano
HAL ID: 739814
ORCID: 0000-0003-3627-3257
hal.structure.identifierNational Cancer Research Institute
dc.contributor.authorCasciano, Ida
hal.structure.identifierNational Cancer Research Institute
dc.contributor.authorCanepa, Pierandrea
hal.structure.identifierNational Cancer Research Institute
dc.contributor.authorRemorgida, Valentino
hal.structure.identifierNational Cancer Research Institute
dc.contributor.authorAnserini, Paola
dc.date.accessioned2020-05-20T10:33:34Z
dc.date.available2020-05-20T10:33:34Z
dc.date.issued2018
dc.identifier.urihttps://basepub.dauphine.fr/handle/123456789/20760
dc.language.isoenen
dc.subjectsmooth endoplasmic reticulum aggregatesen
dc.subjectoocyte dysmorphismen
dc.subjectoocyte physiologyen
dc.subjectmicroarrayen
dc.subjectgene expressionen
dc.titlePresence of aggregates of smooth endoplasmic reticulum in MII oocytes affects oocyte competence: molecular-based evidenceen
dc.typeArticle accepté pour publication ou publié
dc.description.abstractenStudy question: Does the presence of aggregates of smooth endoplasmic reticulum (SERa) impact the transcriptome of human metaphase II (MII) oocytes?.Summary answer: The presence of SERa alters the molecular status of human metaphase II oocytes.What is known already: Oocytes presenting SERa are considered dysmorphic. Oocytes with SERa (SERa+) have been associated with reduced embryological outcome and increased risk of congenital anomalies, although some authors have reported that SERa+ oocytes can lead to healthy newborns. The question of whether or not SERa+ oocytes should be discarded is still open for debate, and no experimental information about the effect of the presence of SERa on the oocyte molecular status is available.en
dc.relation.isversionofjnlnameMolecular Human Reproduction
dc.relation.isversionofjnlvol24en
dc.relation.isversionofjnlissue6en
dc.relation.isversionofjnldate2018-06
dc.relation.isversionofjnlpages310-317en
dc.relation.isversionofdoi10.1093/molehr/gay018en
dc.identifier.urlsitehttps://hal.archives-ouvertes.fr/hal-02351460en
dc.subject.ddclabelMaladiesen
dc.relation.forthcomingnonen
dc.relation.forthcomingprintnonen
dc.description.ssrncandidatenonen
dc.description.halcandidatenonen
dc.description.readershiprechercheen
dc.description.audienceInternationalen
dc.relation.Isversionofjnlpeerreviewednonen
dc.relation.Isversionofjnlpeerreviewednonen
dc.date.updated2020-05-20T10:24:06Z
hal.author.functionaut
hal.author.functionaut
hal.author.functionaut
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